CLD 88 – FENO test

The reference method for FENO testing of neonate, infant and adult patients.

The CLD 88sp FENO analyzer is the reference for continuous, simultaneous measurement and display of NO values, flow rate and volume of the exhaled breath. This sensitive instrument guarantees reproducible and reliable results. It is approved in accordance to CE MDD for clinical use and fully compliant to the 2005 ATS/ERS recommendations for FENO analysis.
One easy operation instrument for all applications, from neonates to adults.

Standard applications:

  • Single breath tests for cooperative patients
  • Multiple breath tests for non-cooperative patients
  • Nasal nitric oxide measurements
  • Offline NO collection kit
  • Alveolar FENO analysis

Your advantage:

  • Noninvasive detection of lung inflammation (e.g. asthma)
  • Verification of anti-inflammatory treatment
  • Detection of non-responders
  • Various flow ranges for research applications (JNO, Calv calculations)

Spiroware 3.0

 

The new SPIROWARE 3.0 is a flexible software tool for easy performing, analyzing and reporting of various FeNO tests. This powerful package is the graphical interface between measurement and excellent documentation of the evaluated data. The future oriented concept fulfils highest requirements of functionality and easy operation. The user guidance and the presented texts are in local language.

ATS / ERS reference:
The analyzer CLD 88sp with SPIROWARE®3.0 is CE MDD (0483) approved for clinical use. The chemiluminescence detection method is only ATS / ERS recommended measurement principle for exhaled Nitric Oxide analysis (FeNO test - Gold Standard) to fulfill the requirements for detection limit, response time and measurement range.

System requirements:
Pentium 3 Processor or better, Microsoft Windows XP with SP3, VISTA or 7, NET Framework 3.5 with SP1, RS232 Interface, 16MByte RAM, 10MB free space on hard disk, XGA-Graphics or better, USB 1.0 or higher

Actual available languages:
English, German, French, Italian, Spanish, Greek and Swedish

Denox 88

NO-free air supply and advanced adaptive flow control to support FENO measurements in accordance to ATS/ERS guideline.

The DENOX 88 module supplies the required NO free air to the patient to perform exhaled NO tests. The integrated adaptive flow control enables even pre-school kids to perform the ATS/ERS recommended single breath test. The expiratory flow control of the DENOX 88 may be adapted to custom specific needs (e.g. 20, 100, 300 ml/min).
For non-cooperative patients the instrument offers the multiple breath test. The continuous flow of NO free air reduces the infant’s work of breathing. The selectable continuous flow rate enables the adjustment to the specific needs of neonates.

Applications:

  • Single breath FENO test for cooperative children/adult patients > 12 years
  • Single breath FENO test for cooperative children < 12 years
  • Multiple breath FENO test for non cooperative patients, e.g. neonates
  • Various flow ranges for NOalv calculations (JNO, Calv, Daw, Caw, FeNO50) 

References:
1. ATS/ERS Recommendations for Standardized Procedures for the Online and Offline Measurement of Exhaled Lower Respiratory Nitric Oxide and Nasal Nitric Oxide, 2005; ATS Board of Directors, December 2004, and by the ERS Executive Committee, June 2004

FeNO offline collection kit

The offline collection kit offers a useful additional option to existing FeNO analyzers. The advantage of offline FeNOmeasurement is that samples can be easily collected at any location, without the need to have the analyzer at site. Gives a more efficient use of the existing FeNO analyzer with collection from several patients simultaneously and less analyzer time per patient is required

Applications:

  •  Children and adult application
  •  Supports single breath technique
  •  Independent testing from NO analyzer
  •  NO free air generation from ambient air
  •  Integrated adaptive flow control and pressure gauge

1. ATS/ERS Recommendations for Standardized Procedures for the Online and Offline Measurement of Exhaled Lower Respiratory Nitric Oxide and Nasal Nitric Oxide, 2005; ATS Board of Directors, December 2004, and by the ERS Executive Committee, June 2004
2. Exhaled nitric oxide in mylar balloons: influence of storage time, humidity and temperature, Bodin / Pijnenburg / Boner / deJongste; Mediators of Inflammation, 12, 47/49 (2003)

Analyzer CLD 88sp - Nitric oxide analyzer with integrated ultrasonic flow measurement

Nitric oxide chemiluminescence (reference method)
Flow ultrasonic transit time
Measurement range 0.1 ppb to 5000 ppb
Detection limit < 0.06 ppb, sample tube type 3
< 0.1 ppb, sample tube type 1
Lag time (software compensated) < 0.9 s, sample tube type 3
< 2.7 s, sample tube type 1
Rise time (0-90%) < 0.1 sec
Fall time (0-90%) < 0.1 sec
Internal sampling rate 40 Hz
Data output rate 15 Hz
Linearity < 1% of full scale
Zero-point drift < 0.5 ppb / 6 h
Interference » 3% of meas. value per vol.-% H2O
» 1% of meas. value per vol.-% CO2
Time resolution 10 ns
Sampling frequency up to 200 Hz
Measurement range up to 15 l/s
Detection limit 0.6 ml/s
Dead space Set 1: 2 ml
Set 2: 10 ml
Temperature range 10 to 40°C
Permitted humidity range 5 to 95% RH (non condensing)
Sample flow rate 110 ml/min ±10 %, sample tube type1 330 ml/min ±10 %, sample tube type3
Cal. gas concentration 0.1 to 4 ppm NO in N2 (1 ppm recommended)
Cal. gas flow rate approx. 600 ml/min
Dimensions 500 mm x 135 mm x 540 mm (Width x Height x Depth)
Weight 24 kg

Pentium 3 type processor or higher, compliant to the Council Directive 93/42 EEC concerning medical devices and the European Safety Standard EN 60601-1, Microsoft Windows XP, VISTA or 7, 16 MByte of RAM, 10MB of free disk space, USB port, XGA or better graphic adapter, RS232 interface


ECO MEDICS reserves the right to change these specifications without notice

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CLD 88sp product sheet >>>

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FeNO offline collection kit product sheet >>>

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Spiroware 3x product sheet >>>

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Cleaning Guidance >>>